Adipokine Serum visfatin level in pregnancy induced hypertension and uncomplicated pregnancy | Shaheen | Pakistan Journal of Medical Sciences
 
میز اداری صندلی مدیریتی صندلی اداری تبلیغات کلیکی میز تلویزیون پاراگلایدر آگهی رایگان محسن چاوشی مسیح و آرش آهنگ جدید لباس زیر شورت زنانه خرید اینترنتی وبلاگدهی گن لاغری

Adipokine Serum visfatin level in pregnancy induced hypertension and uncomplicated pregnancy

Asmat Shaheen, Rubina Nazli Khan, Sadia Fatima, Roshan Ali, Ihsanullah Khan, Salim Khattak

Abstract


Background and Objectives: Hypertensive disorder in pregnancy is the significant disease that badly affects the maternal and fetal prognosis and lead to higher mortality and morbidity in the prenatal period. Visfatin, potentially a new adipokine has emerged having high contribution in pathogenesis of pre-eclampsia. The objective of the study was to find the level of Visfatin in pregnancy induced hypertension and normal pregnant women.

Methods: This study was carried out in tertiary care hospitals, Peshawar from March-October 2014. A total of 234 pregnant women (gestational age >20 weeks) were included in the study with distribution as Preeclampsia (PE=86), Eclampsia (E=74) and control (N=74). Blood was taken for measuring Visfatin level by Enzyme Linked Immunosorbent Assay (ELISA) technique. SPSS version 19 was used for statistical analysis. Student’s t test was performed to evaluate the mean differences in patients and control.

Results: Serum level of visfatin was significantly higher in pregnancy induced hypertension when compared with control (P value <0.001). Comparisons of mean value of visfatin with age group of 21-40 years, body mass index (BMI), primary parous and parity 2-4, gestational age of >36 weeks and both systolic and diastolic blood pressure were highly significant in pregnancy induced hypertension when compared with control (p value <0.001).

Conclusion: Pregnancy induced hypertensive women showed increased level of serum Visfatin than normal pregnant women.

doi: https://doi.org/10.12669/pjms.326.10917

How to cite this:Shaheen A, Nazli R, Fatima S, Ali R, Khan I, Khattak S. Adipokine Serum visfatin level in pregnancy induced hypertension and uncomplicated pregnancy. Pak J Med Sci. 2016;32(6):1419-1424.   doi: https://doi.org/10.12669/pjms.326.10917

 

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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