Hepatosplenic mucormycosis post autologous stem cell transplant

Samia Yasmeen, Omer Waqas, Javeria Munir, Faisal Sultan, Abdul Hameed

Abstract


Mucormycosis is a life threatening fungal infection and remains an important cause of morbidity and mortality in immunocompromised patients after hematopoietic stem cell transplant. We report here a case of hepatosplenic mucormycosis in a patient after autologous stem cell transplant. A young man with anaplastic large cell lymphoma underwent autologous hematopoietic stem cell transplant after achieving complete remission with standard chemotherapy and consolidative radiotherapy. He was found to have incidental hepatosplenic hypodensities on follow up imaging, that were proved to be mucormycosis on histopathology after getting CT-guided biopsy of splenic lesions. He was treated with intravenous amphotericin-B followed by complete radiological resolution of hepatosplenic lesions. Although these infections are often life threatening but limited disease may have better outcome if diagnosed and treated early and aggressively.

doi: https://doi.org/10.12669/pjms.333.12311

How to cite this:Yasmeen S, Waqas O, Munir J, Sultan F, Hameed A. Hepatosplenic mucormycosis post autologous stem cell transplant. Pak J Med Sci. 2017;33(3):776-778.   doi: https://doi.org/10.12669/pjms.333.12311

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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