Clinical osteoporosis probability scoring system: Selection of menopausal women for bone densitometry screening
Abstract
Objectives: To formulate a clinical scoring system for evaluating people at risk of osteoporosis before ordering Bone Mass Densitometry.
Methodology: Eighty two probable clinical osteoporosis related factors were checked in 325 females referred for Bone Mass Densitometry testing in Hamadan province, Iran. The statistical modeling resulted in a clinical osteoporosis probability (COP) scoring system based on 9 factors including: fracture history, drug therapy with thyroid hormone, corticosteroids, estrogen, ca-VitD, number of children, age, BMI and the number of menopausal years.
Results: osteoporosis was found in 62.2%. The osteoporosis probability scoring system cutoff value of 26.8 was selected with 89% sensitivity, 63% specificity, Youden factor of 0.53 and LR=2.4. In this score, osteoporosis probability was 98%. Area under the curve in Roc curve of osteoporosis probability scoring system was 81.4%.
Conclusion: Clinical Osteoporosis Probability scoring system with a 26.8 cutoff value is suggested for osteoporosis prescreening using Bone Mass Densitometry test.
Methodology: Eighty two probable clinical osteoporosis related factors were checked in 325 females referred for Bone Mass Densitometry testing in Hamadan province, Iran. The statistical modeling resulted in a clinical osteoporosis probability (COP) scoring system based on 9 factors including: fracture history, drug therapy with thyroid hormone, corticosteroids, estrogen, ca-VitD, number of children, age, BMI and the number of menopausal years.
Results: osteoporosis was found in 62.2%. The osteoporosis probability scoring system cutoff value of 26.8 was selected with 89% sensitivity, 63% specificity, Youden factor of 0.53 and LR=2.4. In this score, osteoporosis probability was 98%. Area under the curve in Roc curve of osteoporosis probability scoring system was 81.4%.
Conclusion: Clinical Osteoporosis Probability scoring system with a 26.8 cutoff value is suggested for osteoporosis prescreening using Bone Mass Densitometry test.
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