Role of topical antibiotics in prophylaxis against endophthalmitis following intravitreal antibiotics | Asghar | Pakistan Journal of Medical Sciences
 
میز اداری صندلی مدیریتی صندلی اداری تبلیغات کلیکی میز تلویزیون پاراگلایدر آگهی رایگان محسن چاوشی مسیح و آرش آهنگ جدید لباس زیر شورت زنانه خرید اینترنتی وبلاگدهی گن لاغری

Role of topical antibiotics in prophylaxis against endophthalmitis following intravitreal antibiotics

Asfandyar Asghar, Imran Ellhai, Naila Obaid, Ume Sughra

Abstract


Objective: To compare the prophylactic use of antibiotic with placebo to prevent post intra-vitreal endophthalmitis and other complications.

Methods: A prospective, cohort study was conducted at Ophthalmology Department, Fauji Foundation Hospital (FFH), from June 2016 to July 2017. A total of 1082 eyes of 673 patients were enrolled in this study. Patients were selected at non-random and divided into two groups. In Group-I, non – exposed, placebo eye drops were given after intravitreal bevacizumab injections and in Group-II, exposed, ofloxacin eye drops were given after intravitreal bevacizumab injections.

Results: Total 1082 eyes were given intravitreal bevacizumab injection in 673 patients. No patients in Group-I, non – exposed, receiving placebo eye drops developed post intra vitreal endophthalmitis, whereas only 01 (0.1%) patient developed post intravitreal endophthalmitis in Group-II, exposed, receiving ofloxacin eye drops. In inferential statistics the P-value was also statistically insignificant [x2 (1, N=1082) =0.95, P>0.05].

Conclusion: This study showed that topical antibiotic, as a prophylaxis after intravitreal injections has no role in the prevention of post intravitreal endophthalmitis and other complications.

doi: https://doi.org/10.12669/pjms.345.14817

How to cite this:Asghar A, Ellhai I, Obaid N, Sughra U. Role of topical antibiotics in prophylaxis against endophthalmitis following intravitreal antibiotics. Pak J Med Sci. 2018;34(5)1283-1287.   doi: https://doi.org/10.12669/pjms.345.14817

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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