Morphometry of Corpus Callosum Related with Gender and Age: Magnetic Resonance Imaging Study

Abstract

Objective: The corpus callosum (CC) is an important structure of connecting the two cerebral hemispheres. The purpose of this study was to examine the morphometry of the CC of normal cases and its relationship with gender and age.

Methodology: Morphometric measurements of the corpus callosum were made on MR imaging in the mid-sagittal plane in 42 male and 48 female total 90 healthy subjects, age range was 6-17 year-old. Age of the cases were divided into three group as 6-9, 10-13 and 14-17 year-old. The length was measured by drawing a straight line at greatest antero-posterior diamater of CC, a perpendicular at its midline, anterior, posterior and medium segments of CC were measured. In addition as a result of these morphometric measurements index of corpus callosum (CCI) was calculated for every cases. Statistical analysis was performed by One-Way ANOVA- Tukey test, Independent Sample t test, Kruskal-Wallis test and Mann - Whitney U test.

Results: Without considering sex between the age group, antero-posterior, anterior, posterior and medium segments diamaters of CC was found statistically significance (p < 0.05) while analysis of CCI values was not found significant (p > 0.05).

Conclusions: These datas can be used as morphometric guide, for evaluation of the CC specially in years 6-17 age group.