Association of homocysteine with body mass index, blood pressure, HbA1c and duration of diabetes in type 2 diabetics | . | Pakistan Journal of Medical Sciences
 
مبل راحتی صندلی مدیریتی صندلی اداری میز اداری وبلاگدهی گن لاغری بازی اندروید تبلیغات کلیکی آموزش زبان انگلیسی پاراگلایدر مارکت اندروید تور آهنگ محسن چاوشی مسیح و آرش پروتز سینه پروتز باسن پروتز لب میز تلویزیون

Association of homocysteine with body mass index, blood pressure, HbA1c and duration of diabetes in type 2 diabetics

Zulfania ., Adnan Khan, Sohaib Rehman, Tahir Ghaffar

Abstract


Objective: To determine the Homocysteine levels in type 2 diabetics and correlate homocysteine with HbA1c levels, BMI, blood pressure and duration of diabetes.

Methods: This cross-sectional study was conducted in Endocrinology Unit of Hayatabad Medical Complex (HMC) Peshawar and Rehman Medical Institute (RMI) Peshawar over a period of six months from July 2015 to December 2015. Data was recorded and analyzed in SPSS v 20. P value of less than 0.05 was taken as significant. Bivariate Pearson’s correlation test was used to see the relationship between homocysteine and BMI, systolic BP and duration of diabetes.

Results: One hundred twenty five patients were included in our study in which female were 68% and 32% were male with mean age of 51.45±8.37 years. Mean BMI expressed in kg/m2 was 28.71±4.76, mean systolic blood pressure was 130±20.98 mmHg, mean diastolic blood pressure was 83.36±11.28 mmHg and mean duration of diabetes was 7.018±6.18 years. Significant correlation was found between systolic blood pressure (r: 0.239, p: 0.007) and duration of diabetes with homocysteine (r: 0.302, p: 0.001). The correlation of homocysteine with HbA1c and BMI was not significant.

Conclusion: Systolic blood pressure and duration of diabetes showed a significant positive correlation with homocysteine. The correlation of homocysteine with HbA1c was not certain from researcher’s point of view and further studies of larger sample size and longer duration must be conducted to ascertain the association between the two variables. 

doi: https://doi.org/--------------------------------------------

How to cite this:Zulfania, Khan A, Rehman S, Ghaffar T. Association of homocysteine with body mass index, blood pressure, HbA1c and duration of diabetes in type 2 diabetics. Pak J Med Sci. 2018;34(6):---------.   doi: https://doi.org/ -------------------------------------------

This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.


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