Neoplastic transformation of oral lichen plan in young patients

Abstract

Oral lichen plan is a relatively common chronic disorder that occurs in 0.5 to 2.2 percent of the population. Controversy exists in the literature about malignant potential of OLP. Two cases of oral SCC within pre-existing OLP lesions were diagnosed in our department. One of patients was a 31 years old man and nother was a 29 years old woman. Location of the lesions was border of the tongue. Both patients had OLP in oral mucosa for many years. They didn’t have any known risk factors and were healthy. No viral infection was detected by PCR analysis.