A giant interhemispheric lipoma and corpus callosum agenesis

Abstract

The lipomas of the central nervous system are rare lesions and are often located in the midline and in the corpus callosum. They are rarely symptomatic and account for 0.06-0.46 % of intracranial lesions. We report a 5 year old girl who ‘was admitted to the pediatrics clinic due to an intractable complex partial seizure. Biochemical tests for seizure etiology did not reveal any specific cause. Electroencephalography (EEG) showed minimal epileptic activity. Magnetic resonance imaging (MRI) showed that there was a 50x36 mm in diameter mass, and corpus callosum agenesis. Her seizures were controlled with carbamazepine (10mg/kg/day). Although intrahemispheric lipomas are rare, they should be considered in the differential diagnosis of non-febrile seizures in children.