Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 24

 April - June 2008 (Part-I)

Number  2


 

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Effect of pregnancy on total antioxidant
capacity in Nigerian women

Idogun ES1, Odiegwu ME2, Momoh SM3, Okonofua FE4

ABSTRACT

Objective: To assess the total antioxidant capacity during the 3rd trimester of normal pregnancy with the aim of establishing the status of total antioxidant capacity (TAC) in pregnant Nigerians.

Methodology: The subjects consisted of 20 pregnant Nigerian women and 20 non-pregnant women. The cases were age matched with the controls. Total antioxidant capacity was assayed in both the cases and controls using standard methods of total antioxidant capacity assay.

Results: The total antioxidant capacity was lower in the pregnant women 0.84mmol/L compared with the controls 1.00mmol/L, P = 0.007 ‘t’ test.

Conclusion: We observed low total antioxidant capacity in Nigerian women with normal pregnancy. This preliminary report, calls for further investigations.

KEY WORDS: Pregnancy, Oxidative stress, Antioxidant capacity, Nigerian women.

Pak J Med Sci    April - June 2008 (Part-I)    Vol. 24 No. 2    292-295


1. Idogun ES,
Department of Chemical Pathology,
College of Medicine, University of Benin.
Nigeria.
2. Odiegwu ME,
3. Momoh SM,
4. Okonofua FE,
2-4: Department of Obstetrics and Gynecology,
College of Medicine, University of Benin
Benin City, Nigeria.

Correspondence

Dr. E.S Idogun,
Department of Chemical Pathology,
University of Benin Teaching Hospital,
P.M.B 1111, Benin – City,
Nigeria.
E-mail: sylvesteridogun@yahoo.co.uk


* Received for Publication: July 10, 2007
* Revision Received: January 17, 2008
* Revision Accepted: January 20, 2008



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