Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 24

 April - June 2008 (Part-I)

Number  2


 

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Effect of pregnancy on total antioxidant
capacity in Nigerian women

Idogun ES1, Odiegwu ME2, Momoh SM3, Okonofua FE4

ABSTRACT

Objective: To assess the total antioxidant capacity during the 3rd trimester of normal pregnancy with the aim of establishing the status of total antioxidant capacity (TAC) in pregnant Nigerians.

Methodology: The subjects consisted of 20 pregnant Nigerian women and 20 non-pregnant women. The cases were age matched with the controls. Total antioxidant capacity was assayed in both the cases and controls using standard methods of total antioxidant capacity assay.

Results: The total antioxidant capacity was lower in the pregnant women 0.84mmol/L compared with the controls 1.00mmol/L, P = 0.007 t test.

Conclusion: We observed low total antioxidant capacity in Nigerian women with normal pregnancy. This preliminary report, calls for further investigations.

KEY WORDS: Pregnancy, Oxidative stress, Antioxidant capacity, Nigerian women.

Pak J Med Sci    April - June 2008 (Part-I)    Vol. 24 No. 2    292-295


1. Idogun ES,
Department of Chemical Pathology,
College of Medicine, University of Benin.
Nigeria.
2. Odiegwu ME,
3. Momoh SM,
4. Okonofua FE,
2-4: Department of Obstetrics and Gynecology,
College of Medicine, University of Benin
Benin City, Nigeria.

Correspondence

Dr. E.S Idogun,
Department of Chemical Pathology,
University of Benin Teaching Hospital,
P.M.B 1111, Benin City,
Nigeria.
E-mail: sylvesteridogun@yahoo.co.uk


* Received for Publication: July 10, 2007
* Revision Received: January 17, 2008
* Revision Accepted: January 20, 2008



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