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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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EDITORIAL |
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Volume 24 |
April - June 2008 (Part-I) |
Number 2 |
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Aspirin Resistance: An unsettled issue
Maqbool H. JafaryThe issue of aspirin resistance in cardiovascular medicine has been discussed in medical literature since mid-1990s. However, there are several factors awaiting international consensus. Some of the factors include the exact definition of resistance, the specific and sensitive tests for aspirin resistance and the mechanism of resistance. Lack of consensus also makes the assessment of the incidence of aspirin resistance inaccurate. Till such time these issues are settled, the physicians should continue prescribing low-dose aspirin (75-100 mg daily) to high risk cardiovascular disease patients and try to ensure the compliance on the part of the patients as lack of compliance is a major observation responsible for apparent aspirin failure.
KEY WORDS: Aspirin resistance, Cardiovascular disease, compliance.Pak J Med Sci April - June 2008 (Part-I) Vol. 24 No. 2 189-191
Correspondence:
Dr. Maqbool H. Jafary, FRCP
President,
Pakistan Aspirin Foundation
Consultant Physician/Cardiologist,
Karachi Institute of Heart Diseases,
Karachi - Pakistan.
E-mail: maqbool.jafary@gmail.com
* Received for Publication: April 23, 2008
* Revision Accepted: May 10, 2008
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