Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 23

April - June 2007 (Part-II)

Number 3


 

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Association of hypertension and diastolic
dysfunction with type-2 diabetes mellitus

S.M. Sohail Ashraf1, Fasia Basir2

ABSTRACT
Objective: To evaluate the prevalence of hypertension and diastolic dysfunction (LVDD) with normal ejection fraction in type-2 diabetes mellitus.
Method: Two hundred twelve diabetic patients (98 females and 114 males) from January 2005 to June 2006 were enrolled in this study. Their ages ranged from 35 to 65 years with mean age of 55 years. Patients with Diabetes Mellitus Type-2, Hypertension: BP³140/90 (with or without medication) Body Mass Index³30, Waist-Hip ratio>0.90. Left Ventricular Diastolic Dysfunction (LVDD) and Serum Triglyceride and HDL Cholesterol were included.
Result: Out of 212 patients, 104(49%) were found to be hypertensive (both systolic and diastolic) and 12 patients (5.6%) were found to be suffering from isolated systolic hypertension. Hence total number of hypertensive patients was 116 (54.6%). Thirty two patients were found to be suffering from diastolic dysfunction.
Conclusion: Hypertension and Diabetes are interlinked and show how micro and macrovascular complications of diabetes are increased when two conditions occur together. The LVDD is much more prevalent than previously suggested in patients with type-2 diabetes mellitus. Hence LVDD is an early marker of diabetic cardiomyopathy.

KEYWORDS: Diabetes Mellitus Type-2, Hypertension, Diastolic dysfunction.

Pak J Med Sci   May - June 2007   Vol. 23 No. 3    344-348


1. Dr. S.M. Sohail Ashraf DTCD,MCPS,MD
Assistant professor of Medicine
2. Dr. Fasia Basir FCPS
Associate professor of Medicine
1-2: Ziauddin Medical University Hospital
Kemari Campus
Karachi - Pakistan.

Correspondence

Dr. S.M. Sohail Ashraf,
D-87/1, Block # 7,
Gulshan-e-Iqbal,
Karachi - Pakistan.
E-mail: dr.sohailashraf@gmail.com

* Received for Publication: September 7, 2006
* Accepted: December 27, 2006



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