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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Surgical interventions in multidrug-resistant tuberculosis:
retrospective analysis of 27 patients treated at a
Tertiary Level Care Center
Amer Bilal1, Abdul Baseer2,
Mohammad Muslim3, Faridullah4,
Arshad Javaid5, MZ Afridi6, MY Khan7
Abstract
Objective: To assess the results of surgery for Multidrug- Resistant Tuberculosis (MDR-TB).
Methodology: Retrospective analysis was done in 27 cases of multidrug- resistant tuberculosis in whom some surgical interventions were carried out at Department of Thoracic surgery, Lady Reading Hospital Peshawar between the years 2002 to 2007. There were 18 male and 9 female patients in the age group of 14-54 years. All were sputum positive at the time of surgery. Majority of patients were treated with pulmonary resections (pneumonectomy [n=07], bilobectomy [n=08] and lobectomy [n=10]), while primary thoracoplasty with apicolysis was done in two patients. Post operatively 2nd line anti tubercular chemotherapy was prescribed for 24 months.
Results: There was one early and one late death. Postoperative complications were seen in three cases. One patient developed bronchopleural fistula with empyema. At a mean follow-up of one year bacteriological cure was achieved in 24 patients.
Conclusion: Judiciously performed adjuvant surgery can yield excellent long term bacteriological cure with acceptable mortality and morbidity in multidrug-resistant tuberculosis. Morbidity and drug compliance remain as problem areas.
KEY WORDS:
Multidrug resistant-tuberculosis, Pulmonary resection, Thoracoplasty.Pak J Med Sci April - June 2008 (Part-II) Vol. 24 No. 3 351-355
How to cite this article:
Bilal A, Baseer A, Muslim M, Faridullah, Javaid A, Afridi MZ, et al. Surgical interventions in multidrug-resistant tuberculosis: retrospective analysis of 27 patients treated at a Tertiary Level Care Center. Pak J Med Sci 2008;24(3): 351-5.
1. Amer Bilal,
2. Abdul Baseer,
3. Mohammad Muslim,
4. Faridullah,
1-4: Dept. of Thoracic Surgery, PGMI,
Lady Reading Hospital,
Peshawar - Pakistan.
5. Arshad Javaid,
6. MZ Afridi,
7. MY Khan,
5-7: Pulmonology,
PGMI,
Peshawar - Pakistan.
Correspondence
Dr. Amer Bilal
E-mail: aamirct@hotmail.com
* Received for Publication: February 25, 2008
* Revision Received: April 25, 2008
* Revision Accepted: April 29, 2008
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