Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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Volume 24

  April - June 2008 (Part-II)

Number 3


 

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Frequency of anti Toxocara antibodies in school
children with chronic cough and eosinophilia in Ahwaz, Iran

Seyed Mohammad Alavi1, Gholamhossein Sefidgaran2

ABSTRACT

Objectives: To determine the seroprevalence of Toxocara in children having chronic cough.

Methodology: It is a cross sectional study conducted at Ahwaz a city southwest Iran, from Sep 2006 to Dec 2006. Analyses were based on 115 children (randomized cluster sampling) with chronic cough (cough with duration of 2 weeks or more). Laboratory exams; CBC, eosinophils absolute count and tests for intestinal parasites were performed. Eosinophils >500/mm3 were considered as eosinophilia. IgG anti-toxocara antibodies test was carried out by ELISA method for eosinophilic child.

Results: Out of total 115 children 29(25.2) were eosinophilic, among them 10(34.48%) hypereosinophilic and 40 (34.78%) had intestinal parasites. Frequency of Toxocara-IgG in chronic cough, eosinophilic and hypereosinophilic was 13.9%, 55.2% and 80% respectively.

Conclusions: Chronic cough associated eosinophilia among children in Ahwaz may be contributing to Toxocara infection.

KEYWORDS: Chronic cough, Anti-toxocara antibodies, Eosinophilic, Ahwaz.

Pak J Med Sci    April - June 2008 (Part-II)    Vol. 24 No. 3    360-363

How to cite this article:

Alavi SM, Sefidgaran G. Frequency of anti Toxocara antibodies in schoolchildren with chronic cough and eosinophilia in Ahwaz, Iran, 2006. Pak J Med Sci 2008;24(3):360-3.


1. Seyed Mohammad Alavi, MD
Joundishapoor Infectious and
Tropical Diseases Research Center,
2. Gholamhossein Sefidgaran, MS
Management Department of Health College,
1,2: Joundishapour University of Medical Sciences,
Ahwaz - Iran.

Correspondence

Dr. Seyed Mohammad Alavi, MD
Email: alavi1329dr@yahoo.com

* Received for publication: June 23, 2007
* Revision Received: March 17, 2008
* Revision Accepted: March 19, 2008



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