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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Comparative evaluation of the diagnostic results of
Fine-Needle Aspiration (FNA) cytology and pathology
in the assessment of thyroid nodules
Fariba Binesh1, Ali Akbar Salari2
ABSTRACT
Objectives: Fine-needle aspiration has become an accepted and cost-effective procedure for rapid diagnosis of thyroid lesions. The routine use of Fine-needle aspiration has reduced the rate of unnecessary surgery for thyroid nodules. This study was conducted to determine the accuracy of fine-needle aspiration biopsy diagnosis
Methodology: During this cross-sectional study, reports of 600 fine needle aspiration cytology of the thyroid, performed during a period of 11 years (1991-2001) in departments of pathology of Shahid Rahnemoon and Shahid Sadoughi hospitals were reviewed. Pathological diagnosis were available for 28 cases. Cytological reports were classified diagnostically, and histological and cytological correlations were determined. Statistical analysis was performed with SPSS 13 and descriptive tests.
Results: From 600 cases (91 male, 509 female) the cytological diagnosis were as follows: 526 (87.7%) benign, 28 (4.7%) malignant, 10 (1.6%) suspicious and 36 (6%) unsatisfactory. Between benign lesions, goiter and follicular adenoma and between malignant lesions, papillary cell carcinomas were the most common. Malignant nodules were more common in females than males (4.9% versus 3.3%). We identified no false-positive results between malignant FNA and histopathology and so positive predictive value was 100%.
Conclusions: Fine-needle aspiration of the thyroid gland is highly accurate and has a low rate of false-positive diagnosis in case of malignant results.
KEYWORDS: Thyroid Nodule, FNA, Accuracy.
Pak J Med Sci April - June 2008 (Part-II) Vol. 24 No. 3 382-385
How to cite this article:
Binesh F, Salari AA. Comparative evaluation of the diagnostic results of Fine-Needle Aspiration cytology and pathology in the assessment of thyroid nodules. Pak J Med Sci 2008;24(3):382-5.
1. Fariba Binesh, MD,
Assistant Professor of Pathology,
Department of Pathology,
2. Ali Akbar Salari, MD,
Associate Professor of Surgery,
Department of Surgery,
1-2: Shahid Sadoughi Hospital,
Shahid Sadoughi University of
Medical Sciences and Health Service,
Yazd, Iran.
Correspondence
Ali Akbar Salari, MD,
Associate Prof. of Surgery,
Department of Surgery,
Shahid Sadoughi Hospital,
Shahid Sadoughi University of
Medical Sciences and Health Service,
Yazd, Iran.
E-mail: ali_salari@hotmail.com
* Received for Publication: November 26, 2007
* Revision Received: April 9, 2008
* Revision Accepted: May 3, 2008
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