Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

HOME   |   SEARCH   |   CURRENT ISSUE   |   PAST ISSUES

-

ORIGINAL ARTICLE

-

Volume 25

 April - June 2009 (Part-II)

Number  3


 

Full Text
PDF of this Article

Antithrombin levels in healthy Pakistani males

Mahfooz ur Rahman1, Hayee A2

ABSTRACT

Objective: To determine the antigenic concentration and percent functional activity of antithrombin in healthy Pakistani males.

Methodology: Over a period of one year, 50 healthy male volunteers divided into two age groups were tested for antithrombin levels by radial immunodiffusion(RID), at the Departments of Pathology King Edward Medical College and Postgraduate Medical Institute, Lahore. None of them were suffering from any acute or chronic disease, nor were taking any medications. Plasma samples were used to determine the antigenic and derived percent activity from NOR-Partigen* plates supplied by Dade Behring.

Results: The younger group of healthy male volunteers (n=25), mean age 23.5 years showed a higher antithrombin concentration 46.7mg/dl or 155% functional activity: while the older volunteers (n=25), with mean age 44.0 years, showed 42.4 mg/dl concentration or 142% functional activity. The p value was insignificant between the groups (p> 0.05).

Conclusions: The younger healthy individuals in our population show higher antithrombin concentration and functional activity, which tends to decrease insignificantly with age.

KEYWORDS: Antithrombin, Males, Age factors.

Pak J Med Sci    April - June 2009 (Part-II)    Vol. 25 No. 3    345-348

How to cite this article:

Rahman M, Hayee A. Antithrombin levels in healthy Pakistani males. Pak J Med Sci 2009;25(3):345-348.


1. Mahfooz ur Rahman,
Associate Professor of Pathology,
Postgraduate Medical Institute, Lahore - Pakistan.
2. Hayee A
Professor of Pathology,
Fatima Memorial Hospital & Medical College, Lahore.

Correspondence

Dr. Mahfooz ur Rahman,
208-G, Phase-5,
DHA, Lahore - Pakistan.
E-mail: drmur2008@gmail.com

* Received for Publication: January 31, 2009
* Revision Received: March 31, 2009
* Revision Accepted: April 5, 2009



HOME   |   SEARCH   |   CURRENT ISSUE   |   PAST ISSUES

Professional Medical Publications
Room No. 522, 5th Floor, Panorama Centre
Building No. 2, P.O. Box 8766, Saddar, Karachi - Pakistan.
Phones : 5688791, 5689285 Fax : 5689860
pjms@pjms.com.pk