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Volume 23 |
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Volume 23 |
January - March 2007 |
Number 1 |
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Plasma Cell Myeloma in a Tertiary Centre in Niger
Delta Region of Nigeria: Clinicoimmunologic AnalysisCaroline Omoti1, N.K.D. Halim2
ABSTRACT
Objective: To determine the incidence and pattern of presentation of patients with multiple myeloma (MM) in a tertiary health center in Edo state, Niger Delta region of Nigeria noted for its petrochemical industries and gas flare sites.
Design: A retrospective study of 30 cases of MM from 1992 to 2004.
Setting: University of Benin Teaching Hospital, Nigeria.
Main outcome measures: Clinicoimmunologic information in addition to autopsy findings was obtained from case-files. Diagnosis was established according to the standard definition and staged according to the Durie-Salmon clinical staging system.
Results: Advanced stages of the disease (II-III) and performance status scale of 2-4 with pathological fractures were the main form of presentation. Overall median survival was three months (P<0.0001) with 33.3% of the patients surviving at 12 months and 13.3% at 24 months.
Conclusion: Bone pains and anaemia with pathological fractures were the commonest characteristic features with a short three months median survival rate.
KEYWORDS: Multiple myeloma, Incidence, Clinicoimmunologic features.
Pak J Med Sci January - March 2007 Vol. 23 No.1 27-32
1. Dr. Caroline Omoti,
Consultant Hematologist.2. Dr. N.K.D. Halim,
Consultant Hematologist.1-2: Department Of Hematology
University Of Benin Teaching Hospital
P.M.B. 1111, Benin City,
Nigeria.Correspondence:
Dr. Caroline Omoti
E mail: ediomoti@yahoo.com* Received for Publication: February 3, 2006
* Accepted: May 25, 2006
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