Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 23

July - September 2007

Number  4


 

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Influence of gender on familial aggregation of
ADHD in relatives of probands with ADHD

Paria Hebrani1, Fatemeh Behdani2

ABSTRACT

Objective: To assess the influence of gender on familial transmission of ADHD.

Methodology: Two hundred seventy seven probands with ADHD (aged 5-17 years) were screened with clinical interview and the schedule for affective disorders and schizophrenia for School – Age Children Present and Lifetime version (K – SADS – PL). Nine hundred ninty seven first degree relatives (554 parents, 443 siblings) were assessed with interview and K-SADS (for under 18 years) and Wender (for age up to 18 years) for ADHD.

Results: Our findings showed no gender differences in the prevalence of ADHD in relatives of ADHD girls and boys. (prevalence of ADHD Like the boys’ families).

Conclusion: The results suggest that boys and girls do not differ in the familial risk factors which contribute in ADHD and the familial aggregation of ADHD in relatives of probands with ADHD. Although this finding is consistent with prior works which suggest more similarities than differences in the nature of ADHD in boys and girls, they are not conclusive and more controlled studies are needed.

KEYWORDS: ADHD, Gender differences, Genetics.

Pak J Med Sci   July - September 2007   Vol. 23 No. 4   610-613


1. Dr. Paria Hebrani,
Child & Adolescent Psychiatrist,
Assistant Professor,
2. Dr. Fatemeh Behdani,
Assistant Professor,
1-2: Department of Psychiatry,
Mashhad University of Medical Sciences
Mashad - Iran.

Correspondence

Dr. Paria Hebrani,
Horre Ameli Street, Ebne Sina Hospital,
Mashad, Iran.
Email: Phebrani@yahoo.com

* Received for Publication: December 20, 2006
* Accepted: April 2, 2007


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