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Volume 24 |
July - September 2008 |
Number 4 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 24 |
July - September 2008 |
Number 4 |
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Earlobe crease and coronary artery disease
Payman Salamati1, Iraj Nazeri2,
Mehdi Alehossein3,
Kambiz Sotoudeh4, Ahmad Rezaee5
ABSTRACT
Objectives: Diagonal ear lobe crease (ELC) has been introduced as a diagnostic physical sign for coronary artery disease (CAD) and the aim of this study was to evaluate the association between ELC and CAD in Iranians.
Methodology: In a cross- sectional study, 106 consecutive patients, referred from cardiologists for angiography, were studied for presence of ELC and CAD in four academic hospitals in Tehran. ELC categorized based on Ishii classification and CAD defined as at least 50% narrowing in one of the three major epicardial vessels.
Results: The average age in 70 men and 36 women was 50.14±14.11 years. Based on angiographic results, patients were divided in two groups. In 57 patients of CAD positive group, 34 patients had ELC and in 49 patients of CAD negative group only 13 patients had ELC. (P<0.05) After adjusting for age, ELC was a significant predictor of CAD (P<0.05). The severity of ELC (size and unilateral or bilateral) was significantly related to presence of CAD (P<0.05). The observed sensitivity, specificity, positive predictive value and negative predictive value of ELC for diagnosis of CAD were in the following order: 59.6%, 73.5%, 72.3% and 61%
Conclusions: In Iranians, the presence of ELC is associated with CAD.
KEY WORDS: Angiography, Coronary Artery Disease, Diagnostic Test.
Pak J Med Sci July - September 2008 Vol. 24 No. 4 600-603
How to cite this article:
Salamati P, Nazeri I, Alehossein M, Sotoudeh K, Rezaee A. Earlobe crease and coronary artery disease. Pak J Med Sci 2008;24(4):600-3.
1. Payman Salamati,
Assistant Professor of Community Medicine,
2. Iraj Nazeri,
Professor of Cardiology,
3. Mehdi Alehossein,
Assistant Professor of Radiology,
4. Kambiz Sotoudeh,
General Practitioner,
5. Ahmad Rezaee,
Community Medicine Specialist,
1-4: Tehran University of Medical Sciences,
Bahrami Hospital, Shaheed Kiaee St,
Damavand Ave,
Tehran 16417, Iran.
Correspondence
Payman Salamati,
E- mail: psalamati@tums.ac.ir
* Received for Publication: February 20, 2008
* Accepted: June 1, 2008
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