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Volume 25 |
July - September 2009 |
Number 4 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 25 |
July - September 2009 |
Number 4 |
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Outcome and factors associated with hospital mortality in
patients with impaired left ventricular function undergoing
coronary artery bypass grafting: where do we stand?
Mubashir Zareen Khan1, Perveen S2, Ansari JA3, Sami SA4, Furnaz S5, Fatimi SH6
ABSTRACT
Objective: Impaired ventricular function is a known risk factor for mortality after coronary artery bypass grafting however increasingly more patients with impaired ventricular function are referred for surgery. Currently no large data is available from Pakistan regarding this aspect of coronary surgery. Our objectives were to find out the hospital mortality and mid term functional improvement in patients with impaired ventricular function undergoing coronary artery by pass grafting and identify the risk factors for mortality.
Methodology: Retrospective analysis of preoperative, operative and postoperative variables of patients with impaired ventricular function who were operated for isolated first time coronary artery bypass between October 2006 to April 2009.
Results: Total 190 patients with impaired ventricular function underwent isolated first time coronary artery bypass grafting during this period with a male predominance (82.6%). Mean ejection fraction of the group was 25.4±5.3%. Mean predicted mortality on logistic Euro score was 10.9±2.7%. Actual in hospital mortality of the group was 4.7% which is comparable to contemporary published results. Multivariate analysis identified use of intra aortic balloon pump, non use of internal mammary artery and preoperative NYHA functional class as factors associated with mortality.
Conclusion: Coronary artery bypass grafting can be performed in patients with impaired ventricular function with acceptable hospital mortality and mid term functional improvement.
KEY WORDS:
Out come, Factors, Mortality, CABG, Impaired ventricular function.Pak J Med Sci July - September 2009 Vol. 25 No. 4 526-532
How to cite this article:
Khan MZ, Perveen S, Ansari JA, Sami SA, Furnaz S, Fatimi SH. Outcome and factors associated with hospital mortality in patients with impaired left ventricular function undergoing coronary artery bypass grafting: where do we stand?. Pak J Med Sci 2009;25(4):526-532.
1. Khan MZ,
2. Perveen S,
3. Ansari JA
Karachi Institute of Heart Diseases,
Karachi - Pakistan.
4 Sami SA,
5 Furnaz S,
6 Fatimi SH,
1-2, 4-6: Division of Cardiothoracic Surgery,
Aga Khan University Hospital,
Karachi - Pakistan.
Correspondence
Dr Mubashir Zareen Khan
Division of Cardiothoracic Surgery,
Aga Khan University Hospital
Stadium Road,
PO. Box 3500,
Karachi 74800, Pakistan
E Mail: mubashir.khan@aku.edu
* Received for Publication: July 7, 2009
* Revision Received: July 28, 2009
* Revision Accepted: July 29th 2009
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