Pakistan Journal of Medical Sciences

Published by : PROFESSIONAL MEDICAL PUBLICATIONS

ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 26

July - September 2010

Number  3


 

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Association between Helicobacter pylori
seropositivity and Hepatic Encephalopathy

Ramin Behroozian1, Maryam Faramarzpur2, Ezat Rahimi3

ABSTRACT

Objective: The knowledge on Helicobacter pylori (H. pylori) contribution in the pathology of the liver and biliary tract diseases in human is very limited. The aim of this study was to assess the probable association between H. pylori seropositivity and hepatic encephalopathy.

Methodology: This is a case control study conducted through three groups, cirrhotics with hepatic encephalopathy (HE), cirrhotics without HE and healthy controls. All subjects were examined serologically for determination of IgG class antibodies to H. pylori based on ELISA technique.

Results: H. pylori seropositivity was present in 88% cirrhotic patients with hepatic encephalopathy, 86% cirrhotics without hepatic encephalopathy and 66% healthy controls.

Conclusion: According to our results, H. pylori seropositivity rate in cirrhotic patients with or without hepatic encephalopathy was higher than healthy controls. But H. pylori seropositivity rate was not significantly different among cirrhotics with hepatic encephalopathy and those without it.

KEY WORDS: Hepatic Encephalopathy, Cirrhosis, Helicobacter pylori infection.

Pak J Med Sci    July - September 2010    Vol. 26 No. 3    547-550

How to cite this article:

Behroozian R, Faramarzpur M, Rahimi E. Association between Helicobacter pylori seropositivity and Hepatic Encephalopathy. Pak J Med Sci 2010;26(3):547-550


1. Ramin Behroozian, MD,
Associate Professor of Gastroenterology
2. Maryam Faramarzpur, MD,
Internist
3. Ezat Rahimi, MD,
Medical Resident,
1-3: Department of Internal Medicine,
Urmia University of Medical Sciences,
Urmia, Iran.

Correspondence:

Ramin Behroozian,
P.O.Box: 13185-1678, Tehran, Iran.
E-mail: rbehroozian@gmail.com 

* Received for Publication: February 23, 2010

* Revision Received: May 5, 2010

* Final Revision Accepted: May 10, 2010



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