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Volume 23 |
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Volume 23 |
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Number 5 |
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Assessment of serum lipids in Nigerians with
type 2 diabetes mellitus complications
Idogun ES1, Unuigbe EI2, Ogunro PS3, Akinola OT4, Famodu AA5
ABSTRACT
Objective: To assess the serum lipids and lipoprotein cholesterol in patients with complicated type 2 Diabetes Mellitus (DM): Hypertensive diabetics and diabetic nephropathy.
Methodology: This is a cross-sectional study. A total of 52 type 2 DM patients and 20 healthy controls were studied. The patients’ population consisted of 23 normotensive diabetics, 16 hypertensive diabetics and 13 patients with diabetic nephropathy. The serum total cholesterol, HDL-cholesterol and triglycerides were assayed in patients and controls, using standardized assay methods.
Results: The mean serum total cholesterol was higher in patients than controls. The normotensive diabetic patients had the lowest total cholesterol among the patients’ groups 4.01±0.82 mmol/L compared to the hypertensive diabetics 6.01±0.93 mmol/L and the diabetic nephropathy patients 6.90±1.20 mmol/L, (P <0.0001). The prevalence of dyslipidaemia in the patients was between 25%-69%, lowest in the normotensive diabetics and highest in the diabetic nephropathy patients.
Conclusion: We hope that these findings will draw specific attention to the management of dyslipidaemia in patients with complicated type 2 DM especially diabetic nephropathy and hypertensive diabetics.
KEY WORDS: Dyslipidaemia, Type 2 DM Complications, Nigerians.
Pak J Med Sci October - December 2007 (Part-I) Vol. 23 No. 5 708-712
1. Idogun ES,
Department of Chemical Pathology,
2. Unuigbe EI,
Department of Medicine,
1-2: College of Medicine,
University of Benin Teaching Hospital, P.M.B. 1111,
Benin – City, Nigeria.
3. Ogunro PS,
Dept. of Chemical Pathology, College of Health Sciences,
Ladoke Akintola University
Correspondence
Dr. Idogun ES,
E-mail:
sylvesteridogun@yahoo.co.uk
* Received for Publication: November 22, 2006
* Revision Received: December 9, 2006
* Second Revision: August 24, 2007
* Final Revision Accepted: August 30, 2007
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