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Volume 23 |
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Number 5 |
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Volume 23 |
October - December 2007 (Part-I) |
Number 5 |
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The scope o f cardiac complications of
thyrotoxicosis in Lagos, Nigeria
Ogbera AO1, Fasanmade O2, Isiba A3
ABSTRACT
Objective: One of the main complications of thyrotoxicosis (TS) is heart disease, including heart rhythm abnormalities. There is a dearth of reports from sub-saharan Africa hence this study sets out to bridge this gap
Methodology: This was a prospective study carried out for a 24 months period. All subjects with clinical and or biochemical evidence of TS, were followed up and examined for clinical and laboratory features of cardiac complications of thyrotoxicosis.
Results: A total of 103 subjects with TS were seen thus giving an incidence rate of 27%. The Male: Female ratio of the subjects with thyrocardiac disease was 1:5 Frequency of hypertension, arrhythmias and heart failure were 53%, 25% and 42% respectively. Subjects with cardiac complications of TS had florid clinical features of thyrotoxicosis. Echcocardiographic features documented in some of the subjects with heart failure include dilated heart wall, impaired systolic function, reduced ejection fraction and fractional shortening.
Conclusion: Thyrotoxicosis is a notable cause of cardiac morbidity in Nigerians.
KEY WORDS: Thyrotoxicosis, Cardiac complications, Atrial fibrillation.
Pak J Med Sci October - December 2007 (Part-I) Vol. 23 No. 5 671-675
1. Ogbera AO,
Department of Medicine,
Lagos State University Teaching Hospital,
Ikeja, Lagos, Nigeria.
2. Fasanmade O,
Department of Medicine,
Lagos University Teaching Hospital,
Idi-araba, Lagos, Nigeria.
3. Isiba A,
Department of Medicine,
Gbagada General Hospital,
Lagos State, Nigeria
Correspondence
Ogbera AO,
E-mail: oogbera@yahoo.co.uk
* Received for Publication: January 17, 2007
* Revision Received: June 23, 2007
* Revision Accepted: July 5, 2007
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