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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 24 |
October - December 2008 (Part-I) |
Number 5 |
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Role of antibiotic in the
outcome of bronchiolitisCH Rasul1, ARML Kabir2, AKMM Rashid3,
AA Mahboob4, MA Hassan5ABSTRACT
Objective: To estimate the outcome of bronchiolitis with or without antibiotic to justify the avoidance of antibiotic.
Methodology: This was a prospective study done in Khulna Medical College Hospital during six months from October 06 to March 07. All the children below two years admitted in hospital with bronchiolitis were included in the study. The study cases were randomly assigned into one of the three groups - No Antibiotic, Oral Antibiotic and Parenteral Antibiotic. Presenting signs and symptoms were followed up thrice daily to determine the progress of disease. Outcome was estimated by the level of improvement.
Results: Sixty cases of bronchiolitis were included in this study. Most (80%) of them were below six months. The disease was frequently associated with similar problem in siblings (46.7%), noncompliance to exclusive breast feeding (38.3%) and family history of asthma (36.7%). Symptoms like sleeping difficulty and restlessness improved little earlier in No Antibiotic group. On the other hand, signs such as chest indrawing and hepatomegaly improved quicker in Parenteral Antibiotic group although the difference was statistically insignificant. Patchy opacities were found in chest x-ray in 45% cases. None of the study cases died but three of them needed special intervention. Hospital stay was shorter in No Antibiotic group (6.2±1.4) than Oral Antibiotic group (6.7±1.1).
Conclusion: General supportive therapy is highly effective in bronchiolitis and antibiotic does not influence the course of the disease.
KEY WORDS: Bronchiolitis, Antibiotic, Outcome.
Pak J Med Sci October - December 2008 (Part-I) Vol. 24 No. 5 707-711
How to cite this article:
Rasul CH, Kabir A, Rashid AKMM, Mahboob AKMM, Hassan MA. Role of antibiotic in the outcome of bronchiolitis. Pak J Med Sci 2008;24(5):707-11.
1. Choudhury Habibur Rasul, FRCP,
Professor of Paediatrics,
2. ARM Lutful Kabir, FCPS,
Professor of Paediatrics,
Institute of Child & Mother Health,
Dhaka - Bangladesh.
3. AKM Mamunur Rashid MD,
Associate Professor of Paediatrics,
4. Abdullah Al Mahboob, FCPS,
Assistant Professor of Paediatrics,
5. Md Abul Hassan, DCH,
Assistant Professor of Paediatrics,
1,3-5: Khulna Medical College & Hospital,
Khulna - 9000,
Bangladesh.Correspondence
Choudhury Habibur Rasul,
Professor of Paediatrics,
Khulna Medical College & Hospital,
Khulna-9000,
Bangladesh.
Email: chrasul@btcl.net.bd
* Received for Publication: February 21, 2008
* Revision Received: July 28, 2008
* Revision Accepted: July 30, 2008
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