Pakistan Journal of Medical Sciences

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Volume 24

October - December 2008 (Part-I)

Number  5


 

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Evaluation of Hematological and Biochemical
parameters In Snakebite Patients Referred
to Razi Hospital, Ahwaz, Iran

S. Jalal Emam1, Abdolrahim Nikzamir2

ABSTRACT

Objective: To investigate whether hematological and biochemical parameters are associated with increased risk of renal damage in Iranian snakebite patients.

Methodology: In this study 103 snkebite patients (72 males, 27 females) were evaluated. Demographic data, biochemical and hematological tests including Serum creatinine, Creatine Kinase(CK), blood urea nitrogen (BUN), complete blood cell (CBC), prothrombin time(PT), partial thromboplastin time (PTT), urinalysis and rhabdomyolysis were investigated. Hemoglubinuria, myoglubinuria and hematological parameters of the patients in relation to the risk of the renal damage were studied. We also studied the effects of venom on the red blood cell (RBC) and Muscle cells.

Results: Among these patients 50.5% were found to have hemoglubinuria, 68% had red blood cell uria, 40.9% had proteinuria, 29.1% bactriuria, 33% had anemia, 74.8% rhabdomyolysis, 45.6% had myoglubinuria, 12.7% had leukocytosis, 1.9% thrombocytopenia and 65% had coagulopathy.

Conclusion: Rhabdomyolysis and coagulopathy were the most common pathophysiological changes seen in most snakebite patients in this hospital based study.

KEY WORDS: Hemolysis, Snakebite, Rhabdomyolysis, Renal damage.

Pak J Med Sci    October - December 2008 (Part-I)    Vol. 24 No. 5    712-718

How to cite this article:

Emam SJ, Nikzamir A. Evaluation of Hematological And Biochemical parameters In Snakebite Patients Referred To Razi Hospital, Ahwaz, Iran. Pak J Med Sci 2008;24(5):712-18.


1. S. Jalal Emam,
Department of Laboratory Medicine,
Paramedical School,
Ahwaz Jondi shapour University of Medical Sciences,
Ahwaz, Iran.
2. Abdolrahim Nikzamir,
Department of Biochemistry,
Faculty of Medicine,
Ahwaz Jondi shapour University of Medical Sciences,
Ahwaz, Iran.

Correspondence

Abdolrahim Nikzamir
Department of Medical Biochemistry,
Faculty of Medicine,
Ahwaz Jondi shapour University of Medical sciences,
Ahwaz, Iran.
Email: Nikzamirar@yahoo.com

* Received for Publication: December 18, 2007
* Revision Received: July 24, 2008
* Revision Accepted: July 26, 2008



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