|
|
||||
|
Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
||||
|
ISSN 1681-715X |
||||
|
||||
|
- |
||||
|
ORIGINAL ARTICLE |
||||
|
- |
||||
|
Volume 24 |
October - December 2008 (Part-I) |
Number 5 |
||
|
|
||||
|
||||
Study of methicillin resistance in staphylococcus aureus
and species of coagulase negative staphylococci
isolated from various clinical specimensManijeh Mehdinejad1, Ahmad Farajzadeh Sheikh2, Abbas Jolodar3
ABSTRACT
Objective: To identify the Methicillin Resistant Coagulase Negative Staphylococci (MRCONS) and Methicillin Resistant Staphylococcus aureus (MRSA) from clinical specimens and their antimicrobial susceptibility patterns.
Methodology: All strains were recovered from clinical specimens according to 0.5 McFarland standard inoculated on Muller Hinton agar. Antibacterial susceptibility was tested by disks diffusion method.
Results: Of 346 Staphylococci, 250 (72.25%) were identified as methicillin resistance. From these strains, ninety three (37.2%) were MRSA and 157 (62.8%) identified as MRCONS. The highest rate of MRCONS identified in S. haemolyticus and the lowest rate of MRCONS belonged to S. intermedius and S. schleiferi. The susceptibility pattern of MRSA and MRCONS against other antimicrobial agents revealed that the lowest resistance was for vancomycin.
Conclusions: The rate of MRCONS was more than MRSA and vancomycin was the most effective antibiotic against those organisms. As such, this antibiotic is the drug of choice for treatment in such cases.
KEY WORDS: Methicillin Resistance Staphylococcus aureus, Methicillin Resistant Coagulase Negative Staphylococci, Vancomycin.
Pak J Med Sci October - December 2008 (Part-I) Vol. 24 No. 5 719-724
How to cite this article:
Mehdinejad M, Sheikh AF, Jolodar A. Study of methicillin resistance in staphylococcus aureus and species of coagulase negative staphylococci isolated from various clinical specimens. Pak J Med Sci 2008;24(5):719-24.
1. Manijeh Mehdinejad,
Dept. of Microbiology,
School of Medicine,
Ahwaz Jondi Shapour University of Medical Sciences,
Ahwaz, Iran.
2. Ahmad Farajzadeh Sheikh,
Dept. of Microbiology,
School of Medicine,
Ahwaz Jondi Shapour University of Medical Sciences,
Ahwaz, Iran.
3. Abbas Jolodar
Faculty of Veterinary Medicine,
Shahid Chamran University of Ahwaz,
Ahwaz, Iran.Correspondence
Manijeh Mehdinegad,
Dept. of Microbiology, School of Medicine,
Ahwaz Jondishapour University of Medical Sciences,
Ahwaz, Iran.
E-mail: mehdinejad20@yahoo.com
* Received for Publication: July 17, 2007
* Revision Received: March 17, 2008
* 2nd Revision Received: July 8, 2008
* Final Revision Accepted: July 12, 2008
HOME | SEARCH | CURRENT ISSUE | PAST ISSUES
Professional
Medical Publications
Room No. 522, 5th Floor, Panorama Centre
Building No. 2, P.O. Box 8766, Saddar, Karachi - Pakistan.
Phones : 5688791, 5689285 Fax : 5689860
pjms@pjms.com.pk
