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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 24 |
October - December 2008 (Part-I) |
Number 5 |
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Efficacy comparison of splint and oral steroid therapy in
nerve conduction velocity and latency median nerve
in carpal tunnel syndromeNastaran Madjdinasab1, Naser Sharafaddin Zadeh2, Farhad Assarzadegan3,
Armaghan Moravej Ale Ali4, Mohammad Pipelzadeh5ABSTRACT
Objectives: To evaluate the effects of splinting in neutral position of the wrist and oral Prednisolone on neurophysiologic variables in patients with Carpal tunnel syndrome (CTS).
Methodology: This double blind study was carried out in 48 idiopathic CTS patients. They were randomly divided in two groups. Splint group (N=24) used splint for six weeks; and steroid group (N=24) who got oral Prednisolone 20mg/day for two weeks. Electrophysiological evaluations were done initially for having baseline and after 1.5-months follow up. SPSS software (version 11) and independent T test and paired T test were used for statistical analysis.
Results: After six weeks median nerve motor and sensory had distal latency and their conduction velocity improved significantly in both groups (P<0.05). There was no significant difference between both groups due to electro physiologic improvement and clinical improvement.
Conclusion: There was significant electro physiologic improvement in both groups, at six weeks. On comparing the efficacy of the two treatment methods, there was no significant difference between the two.
KEY WORDS: Carpal tunnel syndrome, Neuro-electrophysiology, Oral steroids, Splinting.
Pak J Med Sci October - December 2008 (Part-I) Vol. 24 No. 5 725-728
How to cite this article:
Madjdinasab N, Zadeh NS, Assarzadegan F, Ali AM, Pipelzadeh M. Efficacy comparison of splint and oral steroid therapy in nerve conduction velocity and latency median nerve in carpal tunnel syndrome in south west of Iran. Pak J Med Sci 2008;24(5):725-28.
1. Nastaran Madjdinasab,
Neurologist,
Assistant Professor,
2. Naser Sharafaddin Zadeh,
Neurologist,
Assistant Professor,
3. Farhad Assarzadegan,
Neurologist
4. Armaghan Moravej Ale Ali,
General Physician
5. Mohammad Pipelzadeh,
General Physician,
Neurology Department,
Golestan Hospital,
Ahwaz Jundishapour University of Medical Sciences,
Ahwaz, Iran.
1-4: Clinical Research Center,
Golestan Hospital,
Ahwaz Jundishapour University of Medical Sciences,
Ahwaz, Iran.Correspondence
Nastaran Madjdinasab,
Assistant Professor of Neurology,
Department of Neurology,
Golestan Hospital,
Jundishapur Medical University,
Ahwaz, Iran
E-Mail: N.madjdinasab@gmail.com
* Received for Publication: October 9, 2007
* Revision Received: July 21, 2008
* Revision Accepted: July 30, 2008
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