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Volume 23 |
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Number 6 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 23 |
October - December 2007 (Part-II) |
Number 6 |
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Evaluating causes of acute renal
failure in newborn infants
Gharehbaghi MM1, Peirovifar A MD2
ABSTRACT
Objective: Acute renal failure (ARF) is a common problem in admitted neonates in intensive care units. In most patients ARF accompanies with a predisposing factor such as sepsis, heart failure, perinatal asphyxia or prematurity. The objective of this study was to determine the causes and outcome of ARF in hospitalized newborn infants.
Methodology: In a descriptive cross sectional study we evaluated neonates with ARF who had been hospitalized in Tabriz Children Hospital from March 2004 to September 2005.
Results: There were 85 cases with diagnosed ARF in 3000 hospitalized neonates (2.83%).The male to female ratio in patients with ARF was 2.03:1. Most of involved patients were term (70.6%). The prevalence of renal, pre renal and post renal causes of ARF was 49.4%, 43.5% and 7.1% respectively. The most common predisposing factors for ARF in our study were surgery (43.5%), perinatal asphyxia (36.5%), sepsis (32.9%), respiratory distress syndrome (25.9%), heart failure (20%) and feeding problems (20%). All patients had more than one predisposing factor. Among admitted neonates with ARF mortality rate was 20% and it was significantly higher in patients with assisted ventilation and sepsis (P<0.05).
Conclusion: Early recognition of risk factors such as sepsis, perinatal asphyxia or, perioperative problems and rapid effective treatment of contributing conditions will reduce ARF in neonatal period.
KEY WORDS: Acute renal failure, Newborns, Predisposing factors.
Pak J Med Sci October - December 2007 (Part-II) Vol. 23 No. 6 877-880
1. Dr. MM Gharehbaghi,
Assistant Professor of Pediatrics & Neonatologist
2. Dr. A Peirovifar,
Associate Professor of Anesthesiology and
Intensive Care Medicine,
1,2: Department of Neonatology and
Intensive Care Unit,
Tabriz University of Medical Sciences,
Tabriz – Iran.
Correspondence
Dr. MM Gharehbaghi, MD,
E-mail: gharehbaghimm@yahoo.comv
* Received for Publication: May 31, 2007
* Revision Received: September 1, 2007
* Revision Accepted: September 3, 2007
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