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Volume 23 |
October - December 2007 (Part-II) |
Number 6 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 23 |
October - December 2007 (Part-II) |
Number 6 |
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Intravenous Paracetamol is as effective as Morphine in
Knee Arthroscopic day surgery procedures
Zaka Ullah Khan1, Javaid Iqbal2, Hosny Saleh3, Abeer Mohamed El Deek4
ABSTRACT
Objectives: To conduct a prospective randomized study comparing the analgesic effect of Intravenous Paracetamol with Intravenous Morphine in postoperative pain control of patients undergoing knee arthroscopic surgery as day cases.
Methodology: Eighty four patients were randomised into two groups on the basis of the last digit of their medical number. Odd numbers were given Paracetamol (Group-I) and even Morphine (Group-II). All patients underwent Examination under Anaesthesia (E.U.A) and knee arthroscopy ± a partial menisectomy as day cases and had to stay of a minimum of 4 hours post surgery. A standardize General Anaesthesia was given to both groups. An intra-articular injection of 20mls of 0.5% Marcaine was given to all patients. Postoperative pain was assessed up to 4 hours using the Verbal Rating Scale (V.R.S.). The adverse effects of the drugs were also observed.
Results: Of 84 patients, 76 were males and 8 females. The age range was from 18 to 69 years, weighing from 55 to 90kg. Paracetamol (Group-I) had 43 patients and there were 41 patients in the Morphine (Group-II) Group. The results according to VRS, from 0 to 4 hours showed no difference in the analgesic effect of the two groups, but much less adverse effect were noted in Group-I.
Conclusion: In our study both intravenous Paracetamol and Intravenous Morphine seems to have the same analgesic effect. However, side effects with Intravenous Paracetamol were much less.
KEY WORDS:
Paracetamol, Morphine, Day surgery, Postoperative analgesia.Pak J Med Sci October - December 2007 (Part-II) Vol. 23 No. 6 851-853
1. Dr. Zaka U.
Khan, FRCS (Tr&Orth)
Consultant Orthopaedic Surgeon,
2. Dr Javaid Iqbal, MRCSI
SpR Orthopaedics,
3. Dr Hosny Saleh, FRCSI
Consultant Orthopaedic Surgeon,
4. Dr Abeer Mohamed El Deek, MD
Consultant Anaesthesiologist,
Department of Trauma & Orthopaedics,
Department of Anaesthesia,
1-5: Armed Forces Hospital, Southern region,
Khamis Mushayt, Saudi Arabia.
Correspondence
Dr. Zaka U. Khan,
Armed Forces Hospital, Southern Region,
Department of Trauma & Orthopaedics,
P.O. Box: 101,
Khamis Mushayt,
Kingdom of Saudi Arabia.
E-mail: zaka@doctors.org.uk
* Received for Publication: August 31, 2007
* Revision Received: September 6, 2007
* Revision Accepted: September 24, 2007
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