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ORIGINAL ARTICLE
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Volume 25	October - December 2009 (Part-II)	Number  6
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Hyperamylasemia and acute pancreatitis
following organophosphate poisoning

Arshia Ahmed¹, Imtiaz Begum², Nadia Aquil³,
Sabeen Atif ⁴, Tahir Hussain⁵, Ejaz A Vohra⁶

ABSTRACT

Objective: To determine the frequency of hyperamylasemia and acute pancreatitis following organophosphate poisoning.

Methodology: This is a descriptive study conducted at the Medicine Department, Abbasi Shaheed Hospital Karachi during the period of six months from 16th June 2006 to December 2006. All patients of both sexes and ages above 15 years admitted with a positive history of organophosphate poisoning (OP) were included in the study. A special Proforma was designed to enter all the collected data containing the basic information about the patient, history of recent event and the past history, physical examination and the relevant investigations like complete blood count, serum amylase and lipase, alanine aminotransferase (ALT), lactate dehydrogenase (LDH) and ultrasound abdomen.

Result: Among 90 patients, hyperamylasemia was found in 28 (31%) patients. Hyperlipasemia was seen in nine (10%) patients and pancreatitis was seen in two (2.2%) patients.

Conclusion: Hyperamylasemia is more frequently seen in organophosphate poisoning while two patients proved to have acute pancreatitis as a complication.

KEY WORDS: Organophosphate Poisoning, Acute Pancreatitis, Hyperamylasemia, Hyperlipasemia.

Pak J Med Sci    October - December 2009 (Part-II)    Vol. 25 No. 6    957-961

How to cite this article:

Ahmed A, Begum I, Aquil N, Atif S, Hussain T, Vohra EA. Hyperamylasemia and acute pancreatitis following organophosphate poisoning. Pak J Med Sci 2009;25(6):957-961.

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1. Dr. Arshia Ahmed, FCPS
Senior Registrar
2. Dr. Imtiaz Begum, MRCP.
Assistant Professor
3. Dr. Nadia Aquil, FCPS
Senior Registrar
4. Dr. Sabeen Atif, FCPS
Assistant Professor
5. Prof. Tahir Hussain, MRCP, FRCP
Head of Dept. of Medicine
6. Prof. Ejaz A Vohra, MRCP, FRCP
Dean of Medicine
1-3,6: Ziauddin University Hospital, Karachi - Pakistan.
4-5: Abbasi Shaheed Hospital, Karachi - Pakistan.

Correspondence

Dr. Arshia Ahmed, FCPS (Medicine)
Senior Registrar, Ziauddin University Hospital
B-106 Block 10 Gulshan-e-Iqbal, Karachi.
E-mail: drarshia74@yahoo.com
 
* Received for Publication: June 6, 2009

* Revision Received: November 2, 2009

* Revision Accepted: November 5, 2009

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