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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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Volume 24 |
April - June 2008 (Part-II) |
Number 3 |
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Age as a predictor of Assisted
Reproductive Techniques outcome
Mohammad Ali Karimzadeh1, Sedigheh Ghandi2, Nasim Tabibnejad3
ABSTRACT
Objective: This study evaluated the effect of age on ovarian response to gonadotropin stimulation and the success of IVF & ICSI cycles.
Methodology: In this retrospective analytic study, 280 women undergoing first IVF & ICSI cycles were collected. Patients were divided in three groups: <35 years old, 35 – 39 years and e"40 years old. Stimulation protocol for all patients was long standard protocol.
Results: There were significant decrease in the number of follicles, oocytes retrieved and embryos obtained with increasing age (p<0.05). Fertilization rate did not differ significantly with increasing age (P>0.05). Clinical pregnancy rate were 21.8% in patients < 35, 13.2% in patients 35–39 and 5.9% in e"40 ( p= 0.157 ) and live birth rate were 14.2% in patients < 35, 7.9% in 35–39 and 5.9% in e"40 years old . (p= 0.50)
Conclusions: Clinical pregnancy rate & live birth rate diminished with increasing age.
KEY WORDS: IVF, ICSI, Clinical pregnancy, Live birth.
Pak J Med Sci April - June 2008 (Part-II) Vol. 24 No. 3 378-381
How to cite this article:
Karimzadeh MA, Ghandi S, Tabibnejad N. Age as a predictor of assisted reproductive techniques outcome. Pak J Med Sci 2008;24(3):378-81.
1. Mohammad Ali Karimzadeh,
Professor, Department of Obstetrics and Gynecology,
2. Sedigheh Ghandi,
Assistant Professor,
3. Nasim Tabibnejad,
General practitioner,
1-3: Department of Obstetrics and Gynecology,
Research & Clinical Center for Infertility,
Shahid Sadoughi University of Medical Sciences,
Yazd, Iran.
Correspondence
Mohammad Ali Karimzadeh,
Address: Research & Clinical Center for Infertility,
Bouali Ave, Safaeiyeh,
Yazd, Iran.
E-mail: prof_karimzade@yahoo.com
* Received for Publication: February 8, 2008
* Revision Received: February 11, 2008
* Revision Accepted: March 18, 2008
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