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Published by : PROFESSIONAL MEDICAL PUBLICATIONS |
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ISSN 1681-715X |
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ORIGINAL ARTICLE |
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Volume 21 |
October December 2005 |
Number 4 |
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Prevalence of celiac disease
among patients with iron
deficiency anemia: Personal experience and review of
literature
Abbas Ali Mansoor1 & Sarkis K. Strak2
ABSTRACT
Background: Iron Deficiency Anemia (IDA) is one of the most common presenting features of Celiac Disease (CD).
Objective: The aim of this study is to find the prevalence of CD among patients with otherwise unexplained IDA and review the literatures.
Setting: Al-Faiha & the Basrah Teaching Hospitals in Basrah for the period from May to December 2004.
Methods: This was a cross sectional study of patients with IDA. Gastroduodenoscopy was performed to determine the cause of anemia. Four biopsies were taken from the second part of duodenum. Small intestinal histologic features were interpreted according to the revised Marsh criteria. Total number of patients was 47, 28 males and 19 females, with a mean age of 26.9±13.3 years.
Results: Twenty of 47 patients (42%) had biopsy result consistent with CD. All CD patients were at age of 28 year and below, except one who was 45 year of age. Out of 20 CD patients, 16 were having Marsh grade IIIB and 4 with Marsh grade IIIC. Fourteen were males and 6 were females
Conclusion: All patients with other wise unexplained IDA should have upper gastrointestinal endoscopy with at least four biopsies from the duodenum to exclude CD.
Key words: Celiac Disease (CD), Iron Deficiency Anemia (IDA), duodenal biopsy
Pak J Med Sci October-December 2005 Vol. 21 No. 4 413-416
Correspondence:
Dr. Abbas Ali Mansour
Hattin Post Office Box: 142,
Basrah-42002 IRAQ
E-mail: aambaam@yahoo.com
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