Pakistan Journal of Medical Sciences

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ISSN 1681-715X

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ORIGINAL ARTICLE

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Volume 26

January - March  2010

Number  1


 

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Effects of relaxation and citalopram on severity and
frequency of the symptoms of irritable bowel
syndrome with diarrhea predominance

Solati Dehkordy K1, Adibi P2, Sobhi Gharamaleky N3

ABSTRACT

Objectives: Irritable bowel syndrome (IBS) is the most prevalent functional bowel disorder which is characterized by chronic abdominal pain and altered bowel habit in the absence of any organic disease. This study examined the effects of "relaxation and citalopram" in comparison to "citalopram" alone on alleviating the symptoms of IBS patients with diarrhea predominance.

Methodology: This study was a randomized clinical trial which included 64 IBS patients. The patients were selected according to Rome-III criteria, and were divided into two groups. Bowel Symptoms Severity and Frequency Scale (BSS-FS) was used for evaluation of the patientsí symptoms. Data was analyzed using analysis of covariance (ANCOVA).

Results: There were significant differences in the severity and frequency of IBS symptoms between two groups after the study period regarding BSS-FS (P < 0.05). However, no significant difference was observed at follow-up stage between two groups (P > 0.05).

Conclusion: Relaxation in addition to citalopram in IBS patients with diarrhea predominance can decrease the severity and frequency of symptoms. However, stopping this treatment may lead to recurrence of the symptoms.

KEY WORDS: Irritable bowel syndrome, Relaxation, Citalopram, Bowel Symptoms Severity and Frequency Scale (BSS-FS).

Pak J Med Sci    January - March 2010    Vol. 26 No. 1    88-91

How to cite this article:

Dehkordy SK, Adibi P, Gharamaleky SN. Effects of relaxation and citalopram on severity and frequency of the symptoms of irritable bowel syndrome with diarrhea predominance. Pak J Med Sci 2010;26(1):88-91


1. Solati Dehkordy K, Ph.D
Clinical Psychologist
2. Adibi P, MD
Gastroenterologist,
University of Medical Sciences, Isfahan - Iran.
3. Sobhi Gharamaleky N, Ph.D
Health Psychologist,
1-3. Department of Psychology,
Faculty of Medicine,
Shahrekord University of Medical Sciences,
Hajar Hospital, Shahrekord, Iran.

Correspondence:

Dr. Solati Dehkordy K,
E-mail: kamal_solati@yahoo.com

* Received for Publication: July 24, 2009
* Revision Received: December 15, 2009
* Revision Accepted: January 2, 2010



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