Recurrence rate with use of intraoperative Mitomycin-C versus Conjunctival Autograft following pterygium excision
Abstract
Objectives: To determine the recurrence rate following Conjunctival Autograft versus Mitomycin C for pterygium excision.
Methods: Fifty Patients in this Randomized Clinical Trial who underwent pterygium excision from July 2013 to October 2013 Â at Department of Ophthalmology, Ziauddin University Hospital, Keamari, Karachi were included. All patients underwent detailed ophthalmic examination before surgery. Few drops of lidocaine were instilled, subconjunctival xylocaine 2% was injected. The pterygium was then excised from bulabar conjunctiva and peeled off from the corneal surface. Mitomycin C was applied to bare sclera in group A and Conjunctival autograft taken from superior bulbar conjunctiva of same eye was sutured to the bare sclera in group B. Â Data for pterygium recurrence was collected and analyzed using SPSS version 17.
Results: Among the 50 patients operated 64% (n=32) were male and 36% (n=18) female. Their age ranged from 28 -58 years with mean age 44.8yrs. Right eye was affected in 54% (n= 27) patients and left in 46% (n= 23). In group “A†(intraoperative MMC) conjunctival granuloma was noted in 1(4%), pterygium recurrence 4(16%) and ocular irritation was experienced by 5 (20%) patients. In group “B†(CAG) graft retraction was seen in 2(8%), patients, 1(4%) patients experienced persistent redness over the grafted tissue and pterygium recurrence was seen in 2(8%) patient. All of them were followed at day 1, week1, week 4 and week 12.
Conclusion: Both Conjunctival Autograft and Mitomycin C are effective in reducing the recurrence of pterygium but CAG gives better cosmetic results, the only drawback with it is the duration of the procedure.
doi: http://dx.doi.org/10.12669/pjms.306.5191
How to cite this:Paracha Q, Ayoob M, Dawood Z, Mirza SA. Recurrence rate with use of intraoperative Mitomycin-C versus Conjunctival Autograft following pterygium excision. Pak J Med Sci 2014;30(6):1243-1246. Â doi: http://dx.doi.org/10.12669/pjms.306.5191
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (http://creativecommons.org/licenses/by/3.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
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